If you're getting that strong of an adverse reaction, you really should call your doctor.
Orphenadrine has anti cholinergic properties. This means it affects the parasympathetic nervous system(PNS). The PNS keeps your heart rate slow, keeps your glands(especially salivary) and gastric fluids secreting and other autonomic functions going. A drug with anti cholinergic properties will cause adverse reactions such as: dry mouth (the most common) tachycardia (rapid heart beat), palpitation, urinary hesitancy or retention, blurred vision, dilation of pupils, increased ocular tension, weakness, nausea, vomiting, headache, dizziness, constipation, drowsiness, hypersensitivity reactions, pruritus (itching), hallucinations, agitation, tremor, gastric irritation, and rarely urticaria (hives) and other dermatoses (skin problems).
Since the recommended dosage is one tablet (100mg) twice a day and you've doubled the dosage, it's no wonder you're feeling like shit. Try eating something and if you're still feeling really bad, then I would call your doctor.
And don't mix it with vicodin. Vicodin depresses the central nervous system and this depresses the PNS as well as having some analgesic (pain killing) properties. Not a good combination. I'm surprised you didn't throw your guts up.
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